BIOVIA Direct

The BIOVIA Direct data cartridge, for use with the Oracle database management system, improves R&D efficiency, project team collaboration and IP management. It enables scientists to securely register, search, retrieve, explore and compare novel chemical structures and reactions and macromolecular sequences stored in a single, fully searchable database.

BIOVIA Direct and BIOVIA Pipeline Pilot use the same chemistry engine delivering harmonized results regardless of the workflow – The Same Chemistry Everywhere. BIOVIA Direct is database-tested and offers proven performance with databases containing more than 69 million structures and more than 17 million reactions. It uses a new, hybrid representation that combines the best features of bioinformatics and cheminformatics notations, improving multidisciplinary collaborative research.

• Register and retrieve structures, reactions and biomolecular sequences including peptides, oligonucleotides and oligosaccharides
• Search for and view chemical modifications in sequences
• Develop structure-activity correlations in sequences.

BIOVIA Direct supports the following chemical structure types:

• Small drug-like structures
• Chemically modified structures
• Stereochemistry
• Tetrahedral and non-tetrahedral
• Enhanced atropisomer support
• Biologics, e.g. antibody-drug conjugates (ADCs)
• Polymers
• Mixtures and Formulations
• Variable attachment bonds
• Markush homology groups
• Generic structures for resitration and queries
• Haptic and coordination bond
• Hydrogen bond
• Reactions